Generic Benadryl

(Generic name: Diphenhydramine)

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Benadryl Drug Info


Benadryl Drug Uses: Benadryl is used for the relief of nasal and non-nasal symptoms of various allergic conditions such as seasonal allergic rhinitis. It is also used to treat patients with chronic urticaria. Although antihistamines are the preferred class of drugs in allergic rhinitis, they only reduce symptoms by 40-60%. Diphenhydramine also is used for allergic reactions involving the eyes (allergic conjunctivitis), to prevent or treat active motion sickness, and for mild cases of Parkinsonism, including drug-induced Parkinsonism. The last two uses (motion sickness and Parkinsonism) are based on the anticholinergic effects of diphenhydramine, and not its antihistamine effects. Diphenhydramine also is used as an aid for insomnia.

How to Use Benadryl: Benadryl has its maximal effect about one hour after it is taken. Its effects last for 4 to 6 hours. Therefore, it is often prescribed to be taken every 4 to 6 hours as needed for relief of allergy-related symptoms. When used to combat insomnia, it is prescribed to be taken at bedtime. Patients over the age of 60 years are especially sensitive to the sedating and anticholinergic effects of diphenhydramine, and the dose should be reduced.

Benadryl Precautions: Benadryl has been used extensively in pregnant women; the incidence of fetal malformations is the same as that which would be expected in women who are not taking medications. Additionally, studies in animals suggest no important effects on the fetus. Diphenhydramine, therefore, can be used in pregnancy if the physician feels that it is needed. Benadryl is secreted in breast milk. Because of the risk of stimulation and seizures in infants -- especially newborns and prematures -- antihistamines should not be used by nursing mothers.

Benadryl Drug Interactions: Benadryl adds to (exaggerates) the sedating effects of alcohol and other drugs than can cause sedation such as the benzodiazepine class of anti-anxiety drugs (e.g., Valium, Ativan, Klonopin, Xanax), the narcotic class of pain medications and its derivatives (e.g., Percocet, Vicodin, Dilaudid, Codeine, Darvon), the tricyclic class of antidepressants (e.g., Elavil, Tofranil, Norpramin), and certain antihypertensive medications (e.g., Catapres, Inderal). Diphenhydramine can also intensify the drying effects of other medications with anticholinergic properties (e.g., Bentyl, Urecholine, Probanthine).

Benadryl Possible Side Effects: Benadryl can commonly cause sedation, tiredness, sleepiness, dizziness, disturbed coordination, drying and thickening of oral and other respiratory secretions, and stomach distress. Diphenhydramine may also cause low blood pressure, palpitations, increased heart rate, confusion, nervousness, irritability, blurred vision, double vision, tremor, loss or appetite, or nausea. Diphenhydramine should be used with caution (if at all) in persons with narrow-angle glaucoma, prostatic hypertrophy (enlarged prostate gland), hyperthyroidism, cardiovascular disease, hypertension, and asthma.

Benadryl Overdose: Seek emergency medical attention immediately if an overdose is suspected. Symptoms of Benadryl overdose include: fever, shaking, insomnia, hallucinations, and possibly seizures.

Benadryl Storage: Store Benadryl at room temperature away from moisture and sunlight. Avoid excessive heat. Avoid freezing. Keep out of the reach of children. Dispense of this medicine in a tight, light-resistant container. Do not store Benadryl in the bathroom.

Benadryl Missed Dose: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Disclaimer: The information found on this website is for informational purposes only. It does not cover all possible uses, procedures, safety measures, side effects, or drug interactions of the products. We are not responsible for the accuracy and reliability of this drug information, or any consequences arising from the use of this information. This is only general information and should not be relied on for any purpose.



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